I tend to use setting as a means to convey an immediate context for a protagonist's actions. Generally, my stories take place in the same town--an older, darker version of where I grew up. I establish social lines and divisions, often using the town's geography and physical landscape as a way to make them more believable. Whether that works or not is up for grabs.
But setting is not just geography or weather or texture. It is also comprised of the social structure within it, the interaction, beliefs, and idiosyncrasies of its inhabitants.
I don't think a writer can afford to take setting for granted. One cannot simply announce the city in which characters are interacting and expect a comprehensive knowledge from the reader. I find a precise picture is necessary, with intentional details with an agenda (though the agenda can be ambiguous at first). At least that's what I gravitate towards.
An overlapping commentary on how setting relates seems to help as well. Washington Ave. may be full of gangs, but knowing their motivations (for at least some of them) helps prevent the sense of broad-stroke generalizing.
Steinbeck's non-fiction accounts of his experiences during the Second World War bring it together nicely for me. In particular, a description and summary of the people of Dover (small UK town facing France along the narrowest point of the English Channel):
Dover, with its castle on the hill and its crooked streets, its big, ugly hotels and its secret and dangerous offensive power, is closest of all to the enemy. Dover is full of memory of Wellington and of Napoleon, of the time when Napoleon came down to Calais and looked across the Channel at England and knew that only this little stretch of water interrupted his conquest of the world.
Then Hitler came to the hill above Calais and looked across at the cliffs, and again only the stretch of water stopped the conquest of the world. It is a very little piece of water. On the clear days you can see the hills about Calais, and with a glass you can see the clock tower of Calais. When the guns of Calais fire you cans see the flash, while with the telescope you can see from the castle the guns themselves, and even the tanks deploying on the beach.
There is a quality in the people of Dover that may well be the key to the coming German disaster. They are incorrigibly, incorruptibly unimpressed. The German, with his uniform and his pageantry and his threats and plans, does not impress these people at all. The Dover man has taken perhaps a little more pounding than most, not in great blitzes, but in every-day bombing and shelling, and still he is not impressed.
Jerry is like the weather to him. He complains about it and then promptly goes about what he was doing. Nothing in the world is as important as his garden and, in other days, his lobster pots. Weather and Jerry are alike in that they are inconvenient and sometimes make messes. Surveying a building wrecked by a big shell, he says, "Jerry was bad last night," as he would discuss a windstorm.